Anti-IL-13 Polyclonal Antibody (HW632014)

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100ug

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概述
图片
参考文献
产品说明书

概述

货号

HW632014

品牌

abinScience

描述

Anti-IL13 Polyclonal Antibody (HW632014) is a rabbit polyclonal antibody detecting IL13 in ELISA, IHC, WB. Suitable for Human, Macaca mulatta, Macaca thibetana, and Pan troglodytes.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human IL13 (Pro36-Asn146).

靶标

IL13, NC30, Interleukin-13, IL-13

纯化方式

Purified by antigen affinity column.

Accession号

P35225

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Interleukin-13 (IL13) is a ~15 kDa protein. Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B.

1. Minty, A. et al. (1993) Nature 362, 248-50. PMID: 8096327

2. McKenzie, AN. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 3735-9. PMID: 8097324

3. Defrance, T. et al. (1994) The Journal of experimental medicine 179, 135-43. PMID: 7903680

4. Luttmann, W. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 1678-83. PMID: 8759755

5. Schnyder, B. et al. (1996) Blood 87, 4286-95. PMID: 8639787

6. Miloux, B. et al. (1997) FEBS letters 401, 163-6. PMID: 9013879

7. Kasaian, MT. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 561-9. PMID: 21622864

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for Anti-IL13 Polyclonal Antibody.

参考文献

产品说明书

Anti-IL-13 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-IL-13 Polyclonal Antibody (HW632014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-IL-13 Polyclonal Antibody (HW632014)

概述

图片

参考文献

产品说明书

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