Anti-TPMT Polyclonal Antibody (HW491014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HW491014

品牌

abinScience

描述

Anti-TPMT Polyclonal Antibody (HW491014) is a rabbit polyclonal antibody detecting TPMT in ELISA, IHC, WB. Suitable for Human, Pan troglodytes, and Pongo pygmaeus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human TPMT (Leu26-His227).

靶标

Thiopurine methyltransferase, Thiopurine S-methyltransferase, TPMT

纯化方式

Purified by antigen affinity column.

Accession号

P51580

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Thiopurine S-methyltransferase (TPMT) is a ~28 kDa protein. Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine as the methyl donor. TPMT activity modulates the cytotoxic effects of thiopurine prodrugs. A natural substrate for this enzyme has yet to be identified.

1. Peng, Y. et al. (2008) Biochemistry 47, 6216-25. PMID: 18484748

2. Weinshilboum, RM. et al. (1978) Clinica chimica acta; international journal of clinical chemistry 85, 323-33. PMID: 657528

Note

For research use only.

图片

参考文献

产品说明书

Anti-TPMT Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-TPMT Polyclonal Antibody (HW491014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-TPMT Polyclonal Antibody (HW491014)

概述

图片

参考文献

产品说明书

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