Anti-CRADD Polyclonal Antibody (HX957014)

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概述
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产品说明书

概述

货号

HX957014

品牌

abinScience

描述

Anti-CRADD Polyclonal Antibody (HX957014) is a rabbit polyclonal antibody detecting CRADD in ELISA, IHC, WB. Suitable for Human, Mouse, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CRADD (Met1-Leu140).

靶标

RAIDD, CRADD, RIP-associated protein with a death domain, Caspase and RIP adapter with death domain, Death domain-containing protein CRADD

纯化方式

Purified by antigen affinity column.

Accession号

P78560

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Death domain-containing protein CRADD is a ~22 kDa protein. Adapter protein that associates with PIDD1 and the caspase CASP2 to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis. Also recruits CASP2 to the TNFR-1 signaling complex through its interaction with RIPK1 and TRADD and may play a role in the tumor necrosis factor-mediated signaling pathway.

1. Tinel, A. et al. (2004) Science (New York, N.Y.) 304, 843-6. PMID: 15073321

2. Vakifahmetoglu, H. et al. (2006) Oncogene 25, 5683-92. PMID: 16652156

3. Tinel, A. et al. (2007) The EMBO journal 26, 197-208. PMID: 17159900

4. Park, HH. et al. (2007) Cell 128, 533-46. PMID: 17289572

5. Ahmad, M. et al. (1997) Cancer research 57, 615-9. PMID: 9044836

6. Duan, H. et al. (1997) Nature 385, 86-9. PMID: 8985253

Note

For research use only.

图片

参考文献

产品说明书

Anti-CRADD Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CRADD Polyclonal Antibody (HX957014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CRADD Polyclonal Antibody (HX957014)

概述

图片

参考文献

产品说明书

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