Anti-Human ErbB3/Her3 Recombinant Antibody (SAA0122) (HB116107)

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货号	HB116107
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG1, kappa
克隆号	SAA0122
经测试应用	FCM
靶标	ERBB3, HER3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, Receptor tyrosine-protein kinase erbB-3
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P21860
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Receptor tyrosine-protein kinase erbB-3 (ERBB3/HER3) is a ~148 kDa protein. Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation. 1. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778 2. Kinugasa, Y. et al. (2004) Biochemical and biophysical research communications 321, 1045-9. PMID: 15358134 3. Braunstein, EM. et al. (2016) Leukemia 30, 2242-2245. PMID: 27416908
Note	For research use only.

Flow Cytometry

Flow-cytometry using anti-human ERBB3 antibody. Human SK-BR-3 cell line were stained with an irrelevant antibody (Green Histogram) or an anti-human ERBB3 antibody monoclonal antibody (Catalog # HB116107 , Red Histogram) at a concentration of 20 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human ErbB3/Her3 Recombinant Antibody (SAA0122).pdf

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Anti-Human ErbB3/Her3 Recombinant Antibody (SAA0122) (HB116107)

概述

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参考文献

产品说明书

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重组蛋白

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实验相关试剂

Anti-Human ErbB3/Her3 Recombinant Antibody (SAA0122) (HB116107)

概述

图片

参考文献

产品说明书

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