Anti-Human ALCAM/CD166 Reference Antibody (SAA0066) (HC678107)

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100ug

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货号	HC678107
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG1, kappa
克隆号	SAA0066
靶标	Activated leukocyte cell adhesion molecule, MEMD, CD166 antigen, ALCAM, CD166
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q13740
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	CD166 antigen (ALCAM) is a ~65 kDa protein. Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Acts as a ligand for the LILRB4 receptor, enhancing LILRB4-mediated inhibition of T cell proliferation. 1. Hassan, NJ. et al. (2004) European journal of immunology 34, 930-40. PMID: 15048703 2. Ikeda, K. et al. (2004) The Journal of biological chemistry 279, 55315-23. PMID: 15496415 3. Zimmerman, AW. et al. (2006) Blood 107, 3212-20. PMID: 16352806 4. Iolyeva, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 978-90. PMID: 23169771 5. Escoda-Ferran, C. et al. (2014) FEBS letters 588, 2805-13. PMID: 24945728 6. Bowen, MA. et al. (1995) The Journal of experimental medicine 181, 2213-20. PMID: 7760007 7. Gimferrer, I. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 2262-70. PMID: 15294938 8. Xu, Z. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1207-1219. PMID: 29263213 9. Chitteti, BR. et al. (2014) Blood 124, 519-29. PMID: 24740813
Note	For research use only.

Flow CytoMetry

Flow-cytometry using anti-human CD166 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD166 monoclonal antibody (Catalog: HC678107) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Mouse IgG H&L Polyclonal Antibody, FITC (abinScience: MF690414) and cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human ALCAM/CD166 Reference Antibody (SAA0066).pdf

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Anti-Human ALCAM/CD166 Reference Antibody (SAA0066) (HC678107)

概述

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参考文献

产品说明书

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重组蛋白

抗体

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实验相关试剂

Anti-Human ALCAM/CD166 Reference Antibody (SAA0066) (HC678107)

概述

图片

参考文献

产品说明书

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