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Research Grade Praluzatamab (HC678016)

价格:
规格:
  • 100ug
  • 1mg
数量:
  • 概述
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  • 产品说明书
概述
货号HC678016
品牌abinScience
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Humanized
同种型IgG1-kappa
表达系统Mammalian Cells
克隆类型Monoclonal
靶标Activated leukocyte cell adhesion molecule, MEMD, CD166 antigen, ALCAM, CD166
内毒素水平Please contact the lab for this information.
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q13740
状态Liquid
保存溶液0.01M PBS, pH 7.4.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
别名CX-2009, 2145109-70-0
背景Praluzatamab is a monoclonal antibody targeting the activated leukocyte cell adhesion molecule (ALCAM/CD116). Praluzatamab can be used to synthesize Praluzatamab ravtansine (antibody-drug conjugates). Praluzatamab can be used for research of cancers.
• Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity., PMID:16204050
• Prognostic significance of ALCAM (CD166/MEMD) expression in cutaneous melanoma patients., PMID:26134500
• Predictive impact of activated leukocyte cell adhesion molecule (ALCAM/CD166) in breast cancer., PMID:18172759
• Functional polymorphisms in CD166/ALCAM gene associated with increased risk for breast cancer in a Chinese population., PMID:21293922
• Identification of clinically significant tumor antigens by selecting phage antibody library on tumor cells in situ using laser capture microdissection., PMID:16982673
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • Bioactivity

    Detects CD166/ALCAM in indirect ELISAs.

参考文献

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