货号 | HC678016 |
---|---|
品牌 | abinScience |
种属反应性 | Human |
应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
宿主 | Humanized |
同种型 | IgG1-kappa |
表达系统 | Mammalian Cells |
克隆类型 | Monoclonal |
靶标 | Activated leukocyte cell adhesion molecule, MEMD, CD166 antigen, ALCAM, CD166 |
内毒素水平 | Please contact the lab for this information. |
纯度 | >95% purity as determined by SDS-PAGE. |
纯化方式 | Protein A/G purified from cell culture supernatant. |
Accession号 | Q13740 |
状态 | Liquid |
保存溶液 | 0.01M PBS, pH 7.4. |
稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
别名 | CX-2009, 2145109-70-0 |
背景 | Praluzatamab is a monoclonal antibody targeting the activated leukocyte cell adhesion molecule (ALCAM/CD116). Praluzatamab can be used to synthesize Praluzatamab ravtansine (antibody-drug conjugates). Praluzatamab can be used for research of cancers. • Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity., PMID:16204050 • Prognostic significance of ALCAM (CD166/MEMD) expression in cutaneous melanoma patients., PMID:26134500 • Predictive impact of activated leukocyte cell adhesion molecule (ALCAM/CD166) in breast cancer., PMID:18172759 • Functional polymorphisms in CD166/ALCAM gene associated with increased risk for breast cancer in a Chinese population., PMID:21293922 • Identification of clinically significant tumor antigens by selecting phage antibody library on tumor cells in situ using laser capture microdissection., PMID:16982673 |
Note | For research use only. Not suitable for clinical or therapeutic use. |
Detects CD166/ALCAM in indirect ELISAs.
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