Anti-Human CD245/MYO18A Recombinant Antibody (DY12) (HV061107)

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货号	HV061107
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG1, kappa
克隆号	DY12
靶标	CD245, Myosin containing a PDZ domain, MAJN, SP-R210, Surfactant protein receptor SP-R210, MYO18A, MYSPDZ, Unconventional myosin-XVIIIa, KIAA0216, Molecule associated with JAK3 N-terminus
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q92614
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Unconventional myosin-XVIIIa (CD245/MYO18A) is a ~233 kDa protein. May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. 1. Dippold, HC. et al. (2009) Cell 139, 337-51. PMID: 19837035 2. Ng, MM. et al. (2013) Molecular biology of the cell 24, 796-808. PMID: 23345592 3. Tan, I. et al. (2008) Cell 135, 123-36. PMID: 18854160 4. Yang, L. et al. (2015) PloS one 10, e0126576. PMID: 25965346 5. Yang, CH. et al. (2005) The Journal of biological chemistry 280, 34447-57. PMID: 16087679 6. Sever-Chroneos, Z. et al. (2011) The Journal of biological chemistry 286, 4854-70. PMID: 21123169 7. De Masson, A. et al. (2016) Oncoimmunology 5, e1127493. PMID: 27467939
Note	For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human CD245/MYO18A Antibody (DY12)

产品说明书

Anti-Human CD245/MYO18A Recombinant Antibody (DY12).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

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Anti-Human CD245/MYO18A Recombinant Antibody (DY12) (HV061107)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD245/MYO18A Recombinant Antibody (DY12) (HV061107)

概述

图片

参考文献

产品说明书

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