Anti-Human CD245/MYO18A Recombinant Antibody (DY12), PE (HV061127)

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货号	HV061127
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Mouse
同种型	IgG1, kappa
克隆号	DY12
偶联物	PE
克隆类型	Monoclonal
靶标	CD245, Myosin containing a PDZ domain, MAJN, SP-R210, Surfactant protein receptor SP-R210, MYO18A, MYSPDZ, Unconventional myosin-XVIIIa, KIAA0216, Molecule associated with JAK3 N-terminus
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PE
Accession号	Q92614
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Unconventional myosin-XVIIIa (CD245/MYO18A) is a ~233 kDa protein. May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. 1. Dippold, HC. et al. (2009) Cell 139, 337-51. PMID: 19837035 2. Ng, MM. et al. (2013) Molecular biology of the cell 24, 796-808. PMID: 23345592 3. Tan, I. et al. (2008) Cell 135, 123-36. PMID: 18854160 4. Yang, L. et al. (2015) PloS one 10, e0126576. PMID: 25965346 5. Yang, CH. et al. (2005) The Journal of biological chemistry 280, 34447-57. PMID: 16087679 6. Sever-Chroneos, Z. et al. (2011) The Journal of biological chemistry 286, 4854-70. PMID: 21123169 7. De Masson, A. et al. (2016) Oncoimmunology 5, e1127493. PMID: 27467939
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human CD245/MYO18A Recombinant Antibody (DY12), PE.pdf

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Anti-Human CD245/MYO18A Recombinant Antibody (DY12), PE (HV061127)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD245/MYO18A Recombinant Antibody (DY12), PE (HV061127)

概述

图片

参考文献

产品说明书

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