Anti-Human FGFR4 Recombinant Antibody (U3-17846J6Ye) (HB856107)

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货号	HB856107
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG1, kappa
克隆号	U3-17846J6Ye
靶标	FGFR4, Fibroblast growth factor receptor 4, TKF, FGFR-4, JTK2, CD334
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P22455
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Fibroblast growth factor receptor 4 (CD334/FGFR4) is a ~87 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.
Note	For research use only.

Bioactivity

Detects CD334/FGFR4 in indirect ELISAs.
Western blot

Western blot analysis was performed using anti-CD334/FGFR4 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD334/FGFR4 (Catalog No: HB856011)
Lane 2: negative control

产品说明书

Anti-Human FGFR4 Recombinant Antibody (U3-17846J6Ye).pdf

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Anti-Human FGFR4 Recombinant Antibody (U3-17846J6Ye) (HB856107)

概述

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参考文献

产品说明书

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重组蛋白

抗体

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实验相关试剂

Anti-Human FGFR4 Recombinant Antibody (U3-17846J6Ye) (HB856107)

概述

图片

参考文献

产品说明书

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