Anti-Human FGFR4 Recombinant Antibody (U3-17846J6Ye), APC (HB856137)

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货号	HB856137
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Mouse
同种型	IgG1, kappa
克隆号	U3-17846J6Ye
偶联物	APC
克隆类型	Monoclonal
靶标	FGFR4, Fibroblast growth factor receptor 4, TKF, FGFR-4, JTK2, CD334
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Accession号	P22455
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Fibroblast growth factor receptor 4 (CD334/FGFR4) is a ~87 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human FGFR4 Recombinant Antibody (U3-17846J6Ye), APC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

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Anti-Human FGFR4 Recombinant Antibody (U3-17846J6Ye), APC (HB856137)

概述

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参考文献

产品说明书

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实验相关试剂

Anti-Human FGFR4 Recombinant Antibody (U3-17846J6Ye), APC (HB856137)

概述

图片

参考文献

产品说明书

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