Anti-Mouse Transferrin R/TfR Recombinant Antibody (R17217) (MY036107)

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货号	MY036107
品牌	abinScience
种属反应性	Mouse
应用	FCM
同种型	IgG2a, kappa
克隆号	R17217
靶标	Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, CD71, Tfrc, R17 217.1.3, R17217, TIB-219
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q62351
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Transferrin receptor protein 1 (CD71/TFRC) is a ~85 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Upon stimulation, positively regulates T and B cell proliferation through iron uptake. 1. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240 2. Yang, J. et al. (2024) The Journal of clinical investigation 134. PMID: 38625739
Note	For research use only.

Bioactivity

Detects CD71/TFRC in indirect ELISAs.

产品说明书

Anti-Mouse Transferrin R/TfR Recombinant Antibody (R17217).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

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C₂ (终浓度)

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Anti-Mouse Transferrin R/TfR Recombinant Antibody (R17217) (MY036107)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse Transferrin R/TfR Recombinant Antibody (R17217) (MY036107)

概述

图片

参考文献

产品说明书

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