Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998) (MS714107)

价格:

规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

MS714107

abinScience

种属反应性

Human, Mouse

FCM, WB

IgG2a, kappa

SAA1998

SCA-2, TSA-1, 9804, Retinoic acid-induced gene E protein, TSA1, Lymphocyte antigen 6E, Ly-6E, Stem cell antigen 2, Thymic shared antigen 1, SCA2, RIGE, LY6E, RIG-E

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q64253

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Lymphocyte antigen 6E (LY6E/SCA-2) is a ~14 kDa protein. GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation. Restricts the entry of murine coronavirus, mouse hepatitis virus, by interfering with spike protein-mediated membrane fusion. Also plays an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA). Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I) and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta.

1. Noda, S. et al. (1996) The Journal of experimental medicine 183, 2355-60. PMID: 8642345

2. Kosugi, A. et al. (1998) The Journal of biological chemistry 273, 12301-6. PMID: 9575182

3. Pfaender, S. et al. (2020) Nature microbiology 5, 1330-1339. PMID: 32704094

4. Bacquin, A. et al. (2017) Journal of virology 91. PMID: 28679758

5. Langford, MB. et al. (2018) Scientific reports 8, 3961. PMID: 29500366

6. Wu, M. et al. (2015) The Journal of biological chemistry 290, 24509-18. PMID: 26276394

For research use only.

Western blot

Western blot analysis was performed using anti-LY6E/SCA-2 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human LY6E/SCA-2 (Catalog No: HS714011), 50ng
Lane 2: recombinant human LY6E/SCA-2 (Catalog No: HS714011), 30ng
Lane 3: recombinant human LY6E/SCA-2 (Catalog No: HS714011), 20ng
Lane 4: recombinant human LY6E/SCA-2 (Catalog No: HS714011), 10ng
SDS-PAGE

SDS-PAGE for Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998)

产品说明书

Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998) (MS714107)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998) (MS714107)

概述

图片

参考文献

产品说明书

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