Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998), APC (MS714137)

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100T

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货号	MS714137
品牌	abinScience
种属反应性	Human, Mouse
应用	FCM
宿主	Mouse
同种型	IgG2a, kappa
克隆号	SAA1998
偶联物	APC
克隆类型	Monoclonal
靶标	SCA-2, TSA-1, 9804, Retinoic acid-induced gene E protein, TSA1, Lymphocyte antigen 6E, Ly-6E, Stem cell antigen 2, Thymic shared antigen 1, SCA2, RIGE, LY6E, RIG-E
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC
Accession号	Q64253
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Lymphocyte antigen 6E (LY6E/SCA-2) is a ~14 kDa protein. GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation. Restricts the entry of murine coronavirus, mouse hepatitis virus, by interfering with spike protein-mediated membrane fusion. Also plays an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA). Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I) and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. 1. Noda, S. et al. (1996) The Journal of experimental medicine 183, 2355-60. PMID: 8642345 2. Kosugi, A. et al. (1998) The Journal of biological chemistry 273, 12301-6. PMID: 9575182 3. Pfaender, S. et al. (2020) Nature microbiology 5, 1330-1339. PMID: 32704094 4. Bacquin, A. et al. (2017) Journal of virology 91. PMID: 28679758 5. Langford, MB. et al. (2018) Scientific reports 8, 3961. PMID: 29500366 6. Wu, M. et al. (2015) The Journal of biological chemistry 290, 24509-18. PMID: 26276394
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998), APC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

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Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998), APC (MS714137)

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参考文献

产品说明书

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重组蛋白

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实验相关试剂

Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998), APC (MS714137)

概述

图片

参考文献

产品说明书

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