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Anti-Human IL-13 Recombinant Antibody (SAA0383) (HW632207)

价格:
规格:
  • 50ug
  • 100ug
数量:
  • 概述

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  • 参考文献

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概述
货号HW632207
品牌abinScience
种属反应性Human
应用ELISA, FCM, WB
同种型IgG4, lambda
克隆号SAA0383
经测试应用WB
靶标IL13, NC30, Interleukin-13, IL-13
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P35225
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Interleukin-13 (IL13) is a ~15 kDa protein. Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B.

1. Minty, A. et al. (1993) Nature 362, 248-50. PMID: 8096327
2. McKenzie, AN. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 3735-9. PMID: 8097324
3. Defrance, T. et al. (1994) The Journal of experimental medicine 179, 135-43. PMID: 7903680
4. Luttmann, W. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 1678-83. PMID: 8759755
5. Schnyder, B. et al. (1996) Blood 87, 4286-95. PMID: 8639787
6. Miloux, B. et al. (1997) FEBS letters 401, 163-6. PMID: 9013879
7. Kasaian, MT. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 561-9. PMID: 21622864
NoteFor research use only.
图片
  • Bioactivity

    SEC-HPLC detection for Anti-Human IL13 Antibody (ABS0671).

  • Western blot

    Western blot analysis was performed using anti-IL13 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human IL13 (Catalog No: HW632012)
    Lane 2: negative control

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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