| 货号 | HV162307 |
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| 品牌 | abinScience |
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| 种属反应性 | Human |
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| 应用 | ELISA, FCM, IF, SPR |
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| 同种型 | IgG2a, kappa |
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| 克隆号 | F6 |
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| 靶标 | FzE1, Frizzled-1, hFz1, Fz-1, FZD1, Frizzled-2, FzE2, Fz-2, hFz2, FZD2, Frizzled-5, FzE5, C2orf31, hFz5, FZD5, Fz-5, Frizzled-7, hFz7, FzE3, Fz-7, FZD7, hFz8, Frizzled-8, Fz-8, FZD8 |
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| 内毒素水平 | Please contact with the lab for this information. |
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| 纯度 | >95% as determined by SDS-PAGE. |
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| 纯化方式 | Protein A/G purified from cell culture supernatant. |
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| Accession号 | Q9UP38, Q14332, Q13467, O75084, Q9H461 |
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| 状态 | Liquid |
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| 保存溶液 |
0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
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| 背景 | Frizzled-1 (FZD1) is a ~71 kDa protein. Receptor for Wnt proteins. Activated by WNT3A, WNT3, WNT1 and to a lesser extent WNT2, but apparently not by WNT4, WNT5A, WNT5B, WNT6, WNT7A or WNT7B. Contradictory results showing activation by WNT7B have been described for mouse. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. |
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| Note | For research use only. |
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