| 货号 | HV162317 |
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| 品牌 | abinScience |
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| 种属反应性 | Human |
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| 应用 | ELISA, FCM, IF |
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| 宿主 | Mouse |
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| 同种型 | IgG2a, kappa |
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| 克隆号 | F6 |
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| 偶联物 | FITC |
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| 克隆类型 | Monoclonal |
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| 靶标 | FzE1, Frizzled-1, hFz1, Fz-1, FZD1, Frizzled-2, FzE2, Fz-2, hFz2, FZD2, Frizzled-5, FzE5, C2orf31, hFz5, FZD5, Fz-5, Frizzled-7, hFz7, FzE3, Fz-7, FZD7, hFz8, Frizzled-8, Fz-8, FZD8 |
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| 内毒素水平 | Please contact with the lab for this information. |
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| 相关产品 |
Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), FITC
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| Accession号 | Q9UP38, Q14332, Q13467, O75084, Q9H461 |
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| 状态 | Liquid |
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| 保存溶液 |
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
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| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
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| 背景 | Frizzled-1 (FZD1) is a ~71 kDa protein. Receptor for Wnt proteins. Activated by WNT3A, WNT3, WNT1 and to a lesser extent WNT2, but apparently not by WNT4, WNT5A, WNT5B, WNT6, WNT7A or WNT7B. Contradictory results showing activation by WNT7B have been described for mouse. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. |
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| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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