Anti-Mouse CD37 Recombinant Antibody (252-3#), FITC (MY564117)

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货号	MY564117
品牌	abinScience
种属反应性	Mouse
应用	ELISA, FCM
宿主	Mouse
同种型	IgG2a, kappa
克隆号	252-3#
偶联物	FITC
克隆类型	Monoclonal
靶标	Leukocyte antigen CD37, CD37
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), FITC
Accession号	Q61470
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Leukocyte antigen CD37 (TSPAN26) is a ~31 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Upon ligand binding, two signaling pathways are activated, one acting through phosphorylation by LYN leading to cell death or a survival pathway with activation of GSK3B. Plays an essential role for clustering of integrin ITGA4/ITGB1 and promotes its mobility in the plasma membrane of B-cells. In turn, participates in ITGA4/ITGB1 integrin-mediated antiapoptotic signaling through AKT. 1. Knobeloch, KP. et al. (2000) Molecular and cellular biology 20, 5363-9. PMID: 10891477 2. van Spriel, AB. et al. (2012) Science signaling 5, ra82. PMID: 23150881 3. Gartlan, KH. et al. (2013) European journal of immunology 43, 1208-19. PMID: 23420539 4. Wee, JL. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 195, 5770-9. PMID: 26566675
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Mouse CD37 Recombinant Antibody (252-3#), FITC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

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Anti-Mouse CD37 Recombinant Antibody (252-3#), FITC (MY564117)

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参考文献

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Anti-Mouse CD37 Recombinant Antibody (252-3#), FITC (MY564117)

概述

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参考文献

产品说明书

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