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Anti-Mouse CD37 Recombinant Antibody (252-3#) (MY564107)

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  • 100ug
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概述
货号MY564107
品牌abinScience
种属反应性Mouse
应用ELISA, FCM, Neutralization
同种型IgG2a, kappa
克隆号252-3#
靶标Leukocyte antigen CD37, CD37
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q61470
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Leukocyte antigen CD37 (TSPAN26) is a ~31 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Upon ligand binding, two signaling pathways are activated, one acting through phosphorylation by LYN leading to cell death or a survival pathway with activation of GSK3B. Plays an essential role for clustering of integrin ITGA4/ITGB1 and promotes its mobility in the plasma membrane of B-cells. In turn, participates in ITGA4/ITGB1 integrin-mediated antiapoptotic signaling through AKT.

1. Knobeloch, KP. et al. (2000) Molecular and cellular biology 20, 5363-9. PMID: 10891477
2. van Spriel, AB. et al. (2012) Science signaling 5, ra82. PMID: 23150881
3. Gartlan, KH. et al. (2013) European journal of immunology 43, 1208-19. PMID: 23420539
4. Wee, JL. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 195, 5770-9. PMID: 26566675
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Mouse CD37 Antibody (252-3#)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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