

| 货号 | HW632117 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, FCM |
| 宿主 | Mouse |
| 同种型 | IgG1, kappa |
| 克隆号 | SAA0382 |
| 偶联物 | FITC |
| 克隆类型 | Monoclonal |
| 靶标 | IL13, NC30, Interleukin-13, IL-13 |
| 内毒素水平 | Please contact with the lab for this information. |
| 相关产品 | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), FITC |
| Accession号 | P35225 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Interleukin-13 (IL13) is a ~15 kDa protein. Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B. 1. Minty, A. et al. (1993) Nature 362, 248-50. PMID: 8096327 2. McKenzie, AN. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 3735-9. PMID: 8097324 3. Defrance, T. et al. (1994) The Journal of experimental medicine 179, 135-43. PMID: 7903680 4. Luttmann, W. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 1678-83. PMID: 8759755 5. Schnyder, B. et al. (1996) Blood 87, 4286-95. PMID: 8639787 6. Miloux, B. et al. (1997) FEBS letters 401, 163-6. PMID: 9013879 7. Kasaian, MT. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 561-9. PMID: 21622864 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

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