

| 货号 | MW338117 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Mouse |
| 应用 | FCM, WB |
| 宿主 | Rat |
| 同种型 | IgG1, kappa |
| 克隆号 | DC101 |
| 偶联物 | FITC |
| 克隆类型 | Monoclonal |
| 靶标 | FLK-1, Kinase insert domain receptor, VEGFR2, Fetal liver kinase 1, CD309, Vascular endothelial growth factor receptor 2, Protein-tyrosine kinase receptor flk-1, FLK1, VEGFR-2, KDR |
| 内毒素水平 | Please contact with the lab for this information. |
| 相关产品 | Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), FITC |
| Accession号 | P35918 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Vascular endothelial growth factor receptor 2 (CD309/VEGFR-2) is a ~150 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. CD309 is the therapeutic target of ramucirumab (Cyramza). |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

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