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Anti-Mouse VEGFR2/KDR/Flk-1 Recombinant Antibody (DC101) (MW338107)

通知 · 产品MW338107已停产。
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  • 50ug
  • 100ug
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概述
货号MW338107
品牌abinScience
描述
Anti-Mouse VEGFR2/KDR/Flk-1 Recombinant Antibody (DC101) (MW338107) is a rat monoclonal antibody detecting VEGFR2/KDR/Flk-1 in FCM, Neutralization, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Mouse
应用in vivo blocking of VEGF/VEGFR-2 signaling, in vitro blocking of VEGFR signaling, WB
宿主Rat
克隆类型Monoclonal
同种型IgG1, kappa
克隆号DC101
靶标Vascular endothelial growth factor receptor 2, VEGFR-2, EC:2.7.10.1, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1, CD309, FLK1, VEGFR2
内毒素水平< 1 EU/mg as determined by LAL method.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P35918
状态Liquid
保存溶液 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Vascular endothelial growth factor receptor 2 (CD309/VEGFR-2) is a ~150 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. CD309 is the therapeutic target of ramucirumab (Cyramza).

NoteFor research use only
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Mouse CD309/KDR/VEGFR-2 Antibody (DC101)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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