

| 货号 | MW338107 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Anti-Mouse VEGFR2/KDR/Flk-1 Recombinant Antibody (DC101) (MW338107) is a rat monoclonal antibody detecting VEGFR2/KDR/Flk-1 in FCM, Neutralization, WB. Suitable for Mouse.
Highlights
|
| 种属反应性 | Mouse |
| 应用 | in vivo blocking of VEGF/VEGFR-2 signaling, in vitro blocking of VEGFR signaling, WB |
| 宿主 | Rat |
| 克隆类型 | Monoclonal |
| 同种型 | IgG1, kappa |
| 克隆号 | DC101 |
| 靶标 | Vascular endothelial growth factor receptor 2, VEGFR-2, EC:2.7.10.1, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1, CD309, FLK1, VEGFR2 |
| 内毒素水平 | < 1 EU/mg as determined by LAL method. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P35918 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Vascular endothelial growth factor receptor 2 (CD309/VEGFR-2) is a ~150 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. CD309 is the therapeutic target of ramucirumab (Cyramza). |
| Note | For research use only |

SDS-PAGE for Anti-Mouse CD309/KDR/VEGFR-2 Antibody (DC101)



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