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Anti-Human CD18/ITGB2 Antibody (SAA0815), PerCP (ARO-A10097)

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概述
货号ARO-A10097
品牌ProteoGenix
描述
Anti-Human CD18/ITGB2 Antibody (SAA0815), PerCP [SAA0815] (ARO-A10097) is a human monoclonal antibody detecting Complement receptor C3 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, 95 subunit beta, Integrin beta-2, MFI7, CD18, ITGB2, RHC13101 in ELISA, FCM, WB. Suitable for Human.
Highlights
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, FCM, WB
宿主Human
同种型IgG1
克隆号SAA0815
偶联物PerCP
克隆类型Monoclonal
靶标Complement receptor C3 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, 95 subunit beta, Integrin beta-2, MFI7, CD18, ITGB2, RHC13101
内毒素水平Please contact with the lab for this information.
Accession号P05107
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Integrin beta-2 (CD18/ITGB2) is a ~84 kDa protein. Integrin ITGAL:ITGB2 is a receptor for ICAM1, ICAM2 and ICAM3. Integrin ITGAL:ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM:ITGB2 and ITGAX:ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX:ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM:ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain.

1. de Fougerolles, AR. et al. (1991) The Journal of experimental medicine 174, 253-67. PMID: 1676048
2. Kristóf, E. et al. (2013) Apoptosis : an international journal on programmed cell death 18, 1235-51. PMID: 23775590
3. Lacouture, C. et al. (2024) Nature communications 15, 407. PMID: 38195629
4. Swaim, CD. et al. (2017) Molecular cell 68, 581-590.e5. PMID: 29100055
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6. Van der Vieren, M. et al. (1995) Immunity 3, 683-90. PMID: 8777714
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8. Barber, DF. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 3653-9. PMID: 15356110
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10. Bai, M. et al. (2017) Blood 130, 2092-2100. PMID: 28807980
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human CD18/ITGB2 Antibody (SAA0815), PerCP

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