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Anti-Human CD160 Antibody (H7), FITC (ARO-A10943)

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概述
货号ARO-A10943
品牌ProteoGenix
描述
Anti-Human CD160 Antibody (H7), FITC [H7] (ARO-A10943) is a mouse monoclonal antibody detecting Natural killer cell receptor BY55, CD160 antigen, CD160, BY55 in FCM. Suitable for Human.
Highlights
  • Validated for FCM — Optimized for consistent performance.
种属反应性Human
应用FCM
宿主Mouse
同种型IgG1, kappa
克隆号H7
偶联物FITC
克隆类型Monoclonal
靶标Natural killer cell receptor BY55, CD160 antigen, CD160, BY55
内毒素水平Please contact with the lab for this information.
Accession号O95971
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

CD160 antigen is a ~19 kDa protein. Receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta chain in activated T cells. Receptor for both classical and non-classical MHC class I molecules. In the context of acute viral infection, recognizes HLA-C and triggers NK cell cytotoxic activity, likely playing a role in anti-viral innate immune response. On CD8+ T cells, binds HLA-A2-B2M in complex with a viral peptide and provides a costimulatory signal to activated/memory T cells.

1. Nikolova, M. et al. (2002) International immunology 14, 445-51. PMID: 11978774
2. Rabot, M. et al. (2007) International immunology 19, 401-9. PMID: 17307798
3. Giustiniani, J. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 182, 63-71. PMID: 19109136
4. Le Bouteiller, P. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 16963-8. PMID: 12486241
5. Agrawal, S. et al. (1999) Journal of immunology (Baltimore, Md. : 1950) 162, 1223-6. PMID: 9973372
6. Viganò, S. et al. (2014) PLoS pathogens 10, e1004380. PMID: 25255144
7. Fons, P. et al. (2006) Blood 108, 2608-15. PMID: 16809620
8. Cai, G. et al. (2008) Nature immunology 9, 176-85. PMID: 18193050
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human CD160 Antibody (H7), FITC

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