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Anti-Human CLDN4/Claudin-4 Antibody (SAA0509), FITC (ARO-A10992)

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概述
货号ARO-A10992
品牌ProteoGenix
描述
Anti-Human CLDN4/Claudin-4 Antibody (SAA0509), FITC [SAA0509] (ARO-A10992) is a mouse monoclonal antibody detecting CPER, CLDN4, Williams-Beuren syndrome chromosomal region 8 protein, CPE-R, CPE-receptor, WBSCR8, Claudin-4, Clostridium perfringens enterotoxin receptor, CPETR1 in ELISA, FCM, WB. Suitable for Human.
Highlights
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, FCM, WB
宿主Mouse
同种型IgG2a, kappa
克隆号SAA0509
偶联物FITC
克隆类型Monoclonal
靶标CPER, CLDN4, Williams-Beuren syndrome chromosomal region 8 protein, CPE-R, CPE-receptor, WBSCR8, Claudin-4, Clostridium perfringens enterotoxin receptor, CPETR1
内毒素水平Please contact with the lab for this information.
Accession号O14493
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Claudin-4 (CLDN4) is a ~22 kDa protein. Can associate with other claudins to regulate tight junction structural and functional strand dynamics. May coassemble with CLDN8 into tight junction strands containing anion-selective channels that convey paracellular chloride permeability in renal collecting ducts. May integrate into CLDN3 strands to modulate localized tight junction barrier properties. May disrupt strand assembly of channel-forming CLDN2 and CLDN15 and inhibit cation conductance. Cannot form tight junction strands on its own.

1. Shashikanth, N. et al. (2022) Nature communications 13, 3780. PMID: 35773259
2. Gonschior, H. et al. (2022) Nature communications 13, 4985. PMID: 36008380
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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