Anti-Human Notch-2/Notch-3 Recombinant Antibody (SAA0143), FITC (HC513117)

价格:

规格：

50T
100T

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

货号	HC513117
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Human
同种型	IgG2, kappa
克隆号	SAA0143
偶联物	FITC
克隆类型	Monoclonal
内毒素水平	Please contact with the lab for this information.
相关产品	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), FITC
Accession号	Q04721, Q9UM47
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Neurogenic locus notch homolog protein 2 (NOTCH2/NOTCH3) is a ~265 kDa protein. Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation. 1. Simpson, MA. et al. (2011) Nature genetics 43, 303-5. PMID: 21378985 2. Isidor, B. et al. (2011) Nature genetics 43, 306-8. PMID: 21378989 3. Fukushima, H. et al. (2017) Molecular cell 68, 645-658.e5. PMID: 29149593 4. Zhu, P. et al. (2015) Nature communications 6, 7122. PMID: 25985737
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human Notch-2/Notch-3 Recombinant Antibody (SAA0143), FITC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Notch-2/Notch-3 Recombinant Antibody (SAA0143), FITC (HC513117)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Notch-2/Notch-3 Recombinant Antibody (SAA0143), FITC (HC513117)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价