Anti-Mouse Endosialin/CD248 Recombinant Antibody (G78), FITC (MV681217)

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货号	MV681217
品牌	abinScience
种属反应性	Human, Mouse
应用	ELISA, FCM
宿主	Mouse
同种型	IgG2a, lambda
克隆号	G78
偶联物	FITC
克隆类型	Monoclonal
靶标	Endosialin, TEM1, CD164L1, Tumor endothelial marker 1, CD248
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), FITC
Accession号	Q91V98
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Endosialin (CD248) is a ~81 kDa protein. Cell surface glycoprotein involved in various biological processes including angiogenesis, immune response modulation, and tissue remodeling and repair. Participates in pericyte proliferation through positive modulation of the PDGF receptor signaling pathway. Acts as a scaffold for factor X, triggering allosteric changes and the spatial re-alignment of factor X with the TF-factor VIIa complex, thereby enhancing coagulation activation. Modulates the insulin signaling pathway by interacting with insulin receptor/INSR and by diminishing its capacity to be autophosphorylated in response to insulin. Also regulates LPS-induced inflammatory responses in macrophages by favoring production of proinflammatory cytokines. 1. Opavsky, R. et al. (2001) The Journal of biological chemistry 276, 38795-807. PMID: 11489895 2. Naylor, AJ. et al. (2014) PloS one 9, e107146. PMID: 25243742 3. Benedet, PO. et al. (2024) EBioMedicine 99, 104906. PMID: 38061240 4. Hong, YK. et al. (2019) The Journal of investigative dermatology 139, 2204-2214.e7. PMID: 30986375 5. Kapopara, PR. et al. (2021) Journal of thrombosis and haemostasis : JTH 19, 1932-1947. PMID: 33830628 6. Cheng, TL. et al. (2021) Translational research : the journal of laboratory and clinical medicine 232, 150-162. PMID: 33737161
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Mouse Endosialin/CD248 Recombinant Antibody (G78), FITC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

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Anti-Mouse Endosialin/CD248 Recombinant Antibody (G78), FITC (MV681217)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse Endosialin/CD248 Recombinant Antibody (G78), FITC (MV681217)

概述

图片

参考文献

产品说明书

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