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Anti-Human CD104/ITGB4 Recombinant Antibody (65A12), APC (HB684137)

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规格:
  • 50T
  • 100T
数量:
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概述
货号HB684137
品牌abinScience
种属反应性Human
应用FCM
宿主Mouse
同种型IgG1, kappa
克隆号65A12
偶联物APC
克隆类型Monoclonal
靶标GP150, Integrin beta-4, CD104, ITGB4
内毒素水平Please contact with the lab for this information.
相关产品 Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Accession号P16144
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Integrin beta-4 (CD104/ITGB4) is a ~202 kDa protein. Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling.

1. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778
2. Fujita, M. et al. (2012) The Journal of biological chemistry 287, 12491-500. PMID: 22351760
3. Cedano Prieto, DM. et al. (2017) PloS one 12, e0184285. PMID: 28873464
NoteFor flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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