Anti-Human Integrin alpha L/CD11a Recombinant Antibody (SAA1403), APC (HB805237)

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货号	HB805237
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Human
同种型	IgG4, kappa
克隆号	SAA1403
偶联物	APC
克隆类型	Monoclonal
靶标	CD11A, Leukocyte function-associated molecule 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, CD11 antigen-like family member A, CD11a, ITGAL, Integrin alpha-L
内毒素水平	Please contact with the lab for this information.
相关产品	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4), APC
Accession号	P20701
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Integrin alpha-L (CD11a/ITGAL) is a ~128 kDa protein. Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R. Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. 1. Hermand, P. et al. (2000) The Journal of biological chemistry 275, 26002-10. PMID: 10846180 2. Shimaoka, M. et al. (2003) Cell 112, 99-111. PMID: 12526797 3. de Fougerolles, AR. et al. (1991) The Journal of experimental medicine 174, 253-67. PMID: 1676048 4. Dustin, ML. et al. (1986) Journal of immunology (Baltimore, Md. : 1950) 137, 245-54. PMID: 3086451 5. Ostermann, G. et al. (2002) Nature immunology 3, 151-8. PMID: 11812992 6. Fraemohs, L. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 6259-64. PMID: 15528364 7. Swaim, CD. et al. (2017) Molecular cell 68, 581-590.e5. PMID: 29100055 8. Barber, DF. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 3653-9. PMID: 15356110 9. Lacouture, C. et al. (2024) Nature communications 15, 407. PMID: 38195629 10. Kristóf, E. et al. (2013) Apoptosis : an international journal on programmed cell death 18, 1235-51. PMID: 23775590
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human Integrin alpha L/CD11a Recombinant Antibody (SAA1403), APC.pdf

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Anti-Human Integrin alpha L/CD11a Recombinant Antibody (SAA1403), APC (HB805237)

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参考文献

产品说明书

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实验相关试剂

Anti-Human Integrin alpha L/CD11a Recombinant Antibody (SAA1403), APC (HB805237)

概述

图片

参考文献

产品说明书

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