Anti-Human Desmoglein-3 Recombinant Antibody (DF151), APC (HW575137)

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货号	HW575137
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Mouse
同种型	IgG1, kappa
克隆号	DF151
偶联物	APC
克隆类型	Monoclonal
靶标	Cadherin family member 6, DSG3, Desmoglein-3, 130 kDa pemphigus vulgaris antigen, PVA, CDHF6
内毒素水平	Please contact with the lab for this information.
相关产品	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Accession号	P32926
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Desmoglein-3 (DSG3) is a ~107 kDa protein. A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for adherens and desmosome junction assembly in response to mechanical force in keratinocytes. Required for desmosome-mediated cell-cell adhesion of cells surrounding the telogen hair club and the basal layer of the outer root sheath epithelium, consequently is essential for the anchoring of telogen hairs in the hair follicle. Required for the maintenance of the epithelial barrier via promoting desmosome-mediated intercellular attachment of suprabasal epithelium to basal cells. May play a role in the protein stability of the desmosome plaque components DSP, JUP, PKP1, PKP2 and PKP3. 1. Uttagomol, J. et al. (2019) International journal of molecular sciences 20. PMID: 31835537 2. Koch, PJ. et al. (1998) Journal of cell science 111 ( Pt 17), 2529-37. PMID: 9701552 3. Tsang, SM. et al. (2012) The Journal of pathology 227, 81-93. PMID: 22294297 4. Tsang, SM. et al. (2012) Experimental cell research 318, 2269-83. PMID: 22796473 5. Rötzer, V. et al. (2016) The Journal of investigative dermatology 136, 301-10. PMID: 26763450
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human Desmoglein-3 Recombinant Antibody (DF151), APC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

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Anti-Human Desmoglein-3 Recombinant Antibody (DF151), APC (HW575137)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Desmoglein-3 Recombinant Antibody (DF151), APC (HW575137)

概述

图片

参考文献

产品说明书

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