

| 货号 | ICH8049 |
|---|---|
| 品牌 | IchorBio |
| 描述 |
Enoblituzumab PK ELISA Kit (ICH8049) is a antibody targeting B7-H3 (CD276). Validated for PK ELISA.
Highlights
|
| 应用 | PK ELISA |
| 克隆类型 | Monoclonal |
| 经测试应用 | PK ELISA |
| 靶标 | B7-H3 (CD276) |
| Accession号 | Q5ZPR3 |
| 状态 | Liquid |
| 保存溶液 | Pre-coated 96-well plate, standards, detection antibody, streptavidin-HRP, buffers Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 运输 | Blue Ice |
| 稳定性和存储 | The ELISA Kit should be stored at 2–8°C and is stable for up to 6 months when unopened, unless otherwise stated on the product label or datasheet. Components stored separately may remain stable for up to 12 months under recommended conditions. After opening, keep components tightly capped at 2–8°C. Prepared working solutions should be used on the day of preparation, and repeated freeze-thaw cycles of protein-containing reagents, including reconstituted standards/calibrators, should be avoided. |
| 规格 | Size: 96T |
| 别名 | MG-A271, , 1353485-38-7 |
| 背景 | Enoblituzumab is an Fc-engineered humanized IgG1 monoclonal antibody targeting B7-H3 (CD276), an immune regulatory molecule overexpressed in a wide range of solid tumors. Fc optimization enhances binding to activating Fcγ receptors while reducing interaction with inhibitory Fcγ receptors, thereby increasing antibody-dependent cellular cytotoxicity. Through targeting B7-H3, enoblituzumab promotes immune-mediated tumor cell killing and has been evaluated in multiple solid tumor types, including renal cell carcinoma, bladder cancer, and pancreatic cancer. |
| Note | For research only |

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