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Anti-Human CD50/ICAM3 Recombinant Antibody (SAA1382), PerCP (HW443147)

价格:
规格:
  • 50T
  • 100T
数量:
  • 概述

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  • 参考文献

  • 产品说明书

概述
货号HW443147
品牌abinScience
种属反应性Human
应用FCM
宿主Mouse
同种型IgG1
克隆号SAA1382
偶联物PerCP
克隆类型Monoclonal
靶标CD50, CDw50, Intercellular adhesion molecule 3, ICAM-R, ICAM3, ICAM-3
内毒素水平Please contact with the lab for this information.
相关产品 Mouse IgG1 Recombinant Isotype Control Antibody (HyHEL-10), PerCP
Accession号P32942
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Intercellular adhesion molecule 3 (CD50/ICAM3) is a ~59 kDa protein. Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring apoptotic neutrophil phagocytosis by macrophages. Is also a ligand for integrin ITGAD/ITGB2. Ligand of CD209 on dendritic cells (DC) through an integrin-independent mechanism that requires Ca(2+) and that forms a first contact between DC and resting T cell, facilitating the downstream DC-T cell clustering process and DC-induced proliferation of resting T Cells.

1. Fawcett, J. et al. (1992) Nature 360, 481-4. PMID: 1448173
2. Vazeux, R. et al. (1992) Nature 360, 485-8. PMID: 1448174
3. Kristóf, E. et al. (2013) Apoptosis : an international journal on programmed cell death 18, 1235-51. PMID: 23775590
4. Juan, M. et al. (1993) European journal of immunology 23, 1508-12. PMID: 8325327
5. de Fougerolles, AR. et al. (1993) The Journal of experimental medicine 177, 1187-92. PMID: 8459213
6. Van der Vieren, M. et al. (1995) Immunity 3, 683-90. PMID: 8777714
7. Geijtenbeek, TB. et al. (2000) Cell 100, 575-85. PMID: 10721994
NoteFor flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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