Anti-Human CD85g/LILRA4 Recombinant Antibody (SAA0038), PerCP (HX894147)

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货号	HX894147
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Human
同种型	IgG1, Lambda
克隆号	SAA0038
偶联物	PerCP
克隆类型	Monoclonal
靶标	CD85g, ILT7, Immunoglobulin-like transcript 7, LILRA4, Leukocyte immunoglobulin-like receptor subfamily A member 4, ILT-7, CD85 antigen-like family member G
内毒素水平	Please contact with the lab for this information.
相关产品	Human IgG1, lambda Isotype Control antibody (HyHEL-10), PerCP
Accession号	P59901
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Leukocyte immunoglobulin-like receptor subfamily A member 4 (CD85g/LILRA4) is a ~55 kDa protein. Functions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G. Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as a negative regulator of TLR7 and TLR9 signaling cascades. Down-regulates interferon production in response to interaction with BST2 on HIV-1 infected cells. Activates a signaling cascade in complex with FCER1G that results in phosphorylation of Src family and Syk kinases and thereby triggers mobilization of intracellular Ca(2+). Does not interfere with the differentiation of plasmacytoid dendritic cells into antigen-presenting cells. 1. Cao, W. et al. (2006) The Journal of experimental medicine 203, 1399-405. PMID: 16735691 2. Cao, W. et al. (2009) The Journal of experimental medicine 206, 1603-14. PMID: 19564354 3. Tavano, B. et al. (2014) PloS one 9, e89414. PMID: 24586760 4. Bego, MG. et al. (2015) PLoS pathogens 11, e1005024. PMID: 26172439
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human CD85g/LILRA4 Recombinant Antibody (SAA0038), PerCP.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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Anti-Human CD85g/LILRA4 Recombinant Antibody (SAA0038), PerCP (HX894147)

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Anti-Human CD85g/LILRA4 Recombinant Antibody (SAA0038), PerCP (HX894147)

概述

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参考文献

产品说明书

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