Anti-Human TIM-3 Recombinant Antibody (TSR-022), PE (HV029127)

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货号	HV029127
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Human
同种型	IgG4, kappa
克隆号	TSR-022
偶联物	PE
克隆类型	Monoclonal
靶标	T-cell immunoglobulin mucin receptor 3, HAVcr-2, TIMD-3, T-cell membrane protein 3, HAVCR2, Hepatitis A virus cellular receptor 2, CD366, TIMD3, TIM-3, TIM3, T-cell immunoglobulin and mucin domain-containing protein 3
内毒素水平	Please contact with the lab for this information.
相关产品	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4), PE
Accession号	Q8TDQ0
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Hepatitis A virus cellular receptor 2 (CD366/TIM-3) is a ~33 kDa protein. Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. _x005F_x000D_ _x005F_x000D_ 1. Gorman, JV. et al. (2014) Immunologic research 59, 56-65. PMID: 24825777 _x005F_x000D_ _x005F_x000D_ 2. Monney, L. et al. (2002) Nature 415, 536-41. PMID: 11823861 _x005F_x000D_ _x005F_x000D_ 3. Sánchez-Fueyo, A. et al. (2003) Nature immunology 4, 1093-101. PMID: 14556005 _x005F_x000D_ _x005F_x000D_ 4. Clayton, KL. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 782-91. PMID: 24337741 _x005F_x000D_ _x005F_x000D_ 5. Tomkowicz, B. et al. (2015) PloS one 10, e0140694. PMID: 26492563 _x005F_x000D_ _x005F_x000D_ 6. Gautron, AS. et al. (2014) European journal of immunology 44, 2703-2711. PMID: 24838857 _x005F_x000D_ _x005F_x000D_ 7. Zhu, C. et al. (2005) Nature immunology 6, 1245-52. PMID: 16286920 _x005F_x000D_ _x005F_x000D_ 8. Leitner, J. et al. (2013) PLoS pathogens 9, e1003253. PMID: 23555261 _x005F_x000D_ _x005F_x000D_ 9. Gleason, MK. et al. (2012) Blood 119, 3064-72. PMID: 22323453
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human TIM-3 Recombinant Antibody (TSR-022), PE.pdf

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Anti-Human TIM-3 Recombinant Antibody (TSR-022), PE (HV029127)

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参考文献

产品说明书

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实验相关试剂

Anti-Human TIM-3 Recombinant Antibody (TSR-022), PE (HV029127)

概述

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参考文献

产品说明书

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