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Olokizumab ELISA Kit (KPTX150)

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概述
货号KPTX150
品牌ProteoGenix
描述
Olokizumab ELISA Kit (KPTX150) — Quantitative colorimetric ELISA. for Olokizumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml.
Highlights
  • High Sensitivity — Reliable quantification at low concentrations.
  • Ready-to-Use — Pre-coated plates for streamlined workflow.
样本类型Plasma, Serum
灵敏度0.156 μg/ml
检测范围0.31-5 μg/mL
保存溶液 The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
检测方法Colorimetric
实验类型Quantitative
回收率80-120%
运输2-8 ℃
规格Olokizumab
别名CDP 6038, CAS: 1007223-17-7
背景Olokizumab (CDP6038), a humanized monoclonal antibody (mAb) specific for the interleukin-6 (IL-6) cytokine, is currently in development for the treatment of rheumatoid arthritis (RA). It targets the IL-6 cytokine rather than the receptor, and selectively blocks the final assembly of the signalling complex. In Phase I (healthy volunteers) and IIa (patients with RA on MTX) clinical trials, olokizumab was well tolerated after intravenous and subcutaneous delivery with a median plasma half-life of approximately 31 days, 76% bioavailability and no apparent antidrug antibody-mediated clearance. Olokizumab also markedly reduced free IL-6 levels and suppressed C-reactive protein (CRP) up to 12 weeks after single-dose subcutaneous administration in patients with RA.
NoteFor Research Use Only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Olokizumab ELISA Kit

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