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Cinpanemab ELISA Kit (KPTX227)

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概述
货号KPTX227
品牌ProteoGenix
描述
Cinpanemab ELISA Kit (KPTX227) — Quantitative colorimetric ELISA. for Cinpanemab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL.
Highlights
  • High Sensitivity — Reliable quantification at low concentrations.
  • Ready-to-Use — Pre-coated plates for streamlined workflow.
样本类型Plasma, Serum
检测范围0.31-5 μg/mL
保存溶液 The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

检测方法Colorimetric
实验类型Quantitative
回收率80-120%
运输2-8 ℃
规格Cinpanemab
别名BIIB-054, CAS: 2094516-02-4
背景Cinpanemab is a human-derived monoclonal antibody directed against α-synuclein. Genetic and pathology evidence implicate this protein in the molecular pathogenesis of Parkinson's disease (PD) and other α-synucleinopathies such as dementia with Lewy bodies (DLB). In 2010, Biogen licensed cinpanemab from Neurimmune. The antibody was generated with reverse translational medicine technology from naturally occurring, presumably protective antibodies found in healthy aged donors, as were aducanumab and other antibodies in the Biogen-Neurimmune partnership. The antibody, previously known as BIIB054, binds to α-synuclein residues 1-10, with 800-fold higher affinity for aggregated over monomeric α-synuclein. The antibody inhibits α-synuclein spreading in cell-based assays, and slows pathology and motor symptoms in mice (Weihofen et al., 2019).
NoteFor Research Use Only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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