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Dilpacimab ELISA Kit (KPTX277)

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概述
货号KPTX277
品牌ProteoGenix
样本类型Plasma, Serum
检测范围0.31-5 μg/mL
保存溶液 The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

检测方法Colorimetric
实验类型Quantitative
回收率80-120%
运输2-8 ℃
规格Dilpacimab
别名ABT-165, PR-1283233, CAS: 1791420-09-1
背景Dilpacimab (formerly ABT-165), a novel dual-variable domain immunoglobulin, targets both delta-like ligand 4 (DLL4) and VEGF pathways. Here, we present safety, pharmacokinetic (PK), pharmacodynamic (PD), and preliminary efficacy data from a phase I study (trial registration ID: NCT01946074) of dilpacimab in patients with advanced solid tumors. Eligible patients (≥18 years) received dilpacimab intravenously on days 1 and 15 in 28-day cycles at escalating dose levels (range, 1.25–7.5 mg/kg) until progressive disease or unacceptable toxicity.
NoteFor Research Use Only.
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