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Talacotuzumab ELISA Kit (DB714018)

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  • 96T
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概述
货号DB714018
品牌abinScience
样本类型Plasma, Serum
灵敏度0.156 μg/ml
检测范围0.31-5 μg/mL
Accession号P26951
应用ELISA
检测方法Colorimetric
实验类型Quantitative
回收率80-120%
运输2-8 ℃
稳定性和存储The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
规格

Talacotuzumab

别名CSL-362-AML, CSL362, JNJ-56022473, 1826831-79-1
背景Talacotuzumab (TAL, JNJ-56022473) is an IgG1 monoclonal antibody targeting CD123 preferentially via antibody-dependent cellular cytotoxicity (ADCC) mediated by natural killer (NK) cells and has been shown to induce potent in vitro ADCC against IL3RA-expressing AML blasts/LSC and to reduce leukemic cell growth in murine xenograft models of human AML. In addition, the antibody inhibits signaling by IL-3, the main ligand of CD123, to reduce the proliferation of leukemic progenitor cells.
NoteFor Research Use Only.
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