

| 货号 | HV029018 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Human TIM-3 ELISA Kit (HV029018) — Quantitative sandwich ELISA for TIM-3.
|
| 样本类型 | Cell culture supernates, serum, and plasma |
| 灵敏度 | 5.98 pg/mL |
| 检测范围 | 31.3-2,000 pg/mL |
| 种属反应性 | Human |
| 靶标 | T-cell immunoglobulin and mucin domain-containing protein 3 / TIM-3 |
| Accession号 | Q8TDQ0 |
| 应用 | ELISA |
| 检测方法 | Colorimetric |
| 实验类型 | Sandwich |
| 精准度 | Intra-CV and Inter-CV < 15% |
| 回收率 | 80-120% |
| 运输 | 2-8 ℃ |
| 稳定性和存储 | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
| 背景 | Hepatitis A virus cellular receptor 2 (CD366/TIM-3) is a ~33 kDa protein. Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. 1. Gorman, JV. et al. (2014) Immunologic research 59, 56-65. PMID: 24825777 2. Monney, L. et al. (2002) Nature 415, 536-41. PMID: 11823861 3. Sánchez-Fueyo, A. et al. (2003) Nature immunology 4, 1093-101. PMID: 14556005 4. Clayton, KL. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 782-91. PMID: 24337741 5. Tomkowicz, B. et al. (2015) PloS one 10, e0140694. PMID: 26492563 6. Gautron, AS. et al. (2014) European journal of immunology 44, 2703-2711. PMID: 24838857 7. Zhu, C. et al. (2005) Nature immunology 6, 1245-52. PMID: 16286920 8. Leitner, J. et al. (2013) PLoS pathogens 9, e1003253. PMID: 23555261 9. Gleason, MK. et al. (2012) Blood 119, 3064-72. PMID: 22323453 |
| Note | For research use only |

Standard Curve of Human TIM-3 ELISA Kit



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