Rolinsatamab ELISA Kit (DB801018)

Name: Rolinsatamab ELISA Kit
Brand: abinScience
SKU: DB801018
Availability: InStock

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概述
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参考文献
产品说明书

概述

货号	DB801018
品牌	abinScience
样本类型	Plasma, Serum
灵敏度	0.156 μg/ml
检测范围	0.31-5 μg/mL
Accession号	P16471
应用	ELISA
检测方法	Colorimetric
实验类型	Quantitative
回收率	80-120%
运输	2-8 ℃
稳定性和存储	The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
规格	Rolinsatamab
别名	PR-1594804, h16f, ABBV-176, DC-1630993, h16f, Rolinsatamab talirine, 2095467-30-2
背景	Prolactin receptor (Rolinsatamab) is a ~69 kDa protein. This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.
文献	1. Anderson MG, et al. ABBV-176, a PRLR antibody drug conjugate with a potent DNA-damaging PBD cytotoxin and enhanced activity with PARP inhibition. BMC Cancer. 2021;21(1):681. Published 2021 Jun 9. [DB801018] 2. Lemech C, et al. A first-in-human, phase 1, dose-escalation study of ABBV-176, an antibody-drug conjugate targeting the prolactin receptor, in patients with advanced solid tumors. Invest New Drugs. 2020;38(6):1815-1825. [DB801018] 3. Mukherjee A, et al. Targeted Therapy in Breast Cancer: Advantages and Advancements of Antibody-Drug Conjugates, a Type of Chemo-Biologic Hybrid Drugs. Cancers (Basel). 2024;16(20):3517. Published 2024 Oct 17. [DB801018] 4. Chervin AS, et al. ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies. Mol Cancer Ther. 2023;22(8):903-912. [DB801018] 5. Zhang J, et al. The immunotoxin targeting PRLR increases tamoxifen sensitivity and enhances the efficacy of chemotherapy in breast cancer. J Exp Clin Cancer Res. 2024;43(1):173. Published 2024 Jun 20. View More [DB801018]
Note	For Research Use Only.

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参考文献

产品说明书

Rolinsatamab ELISA Kit.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Rolinsatamab ELISA Kit (DB801018)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Rolinsatamab ELISA Kit (DB801018)

概述

图片

参考文献

产品说明书

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