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InVivoMAb Anti-HCV Envelope glycoprotein E2 Antibody (HC84.26) (VK681020)

价格:
规格:
  • 100ug
  • 1mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号VK681020
品牌abinScience
描述
InVivoMAb Anti-HCV NS1/gp68/gp70/E2 Antibody (HC84.26) [HC84.26] (VK681020) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
种属反应性Hepatitis C Virus (HCV)
应用ELISA, Neutralization
宿主Human
同种型IgG1
克隆号HC84.26
克隆类型Monoclonal
经测试应用WB
靶标Genome polyprotein, Envelope glycoprotein E2, NS1, gp68, gp70
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
相关产品 pH 7.4 Dilution Buffer
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P27958
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Genome polyprotein (NS1/gp68) is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable).

1. Ivanyi-Nagy, R. et al. (2008) Nucleic acids research 36, 712-25. PMID: 18033802
2. Anjum, S. et al. (2013) Molecular medicine reports 8, 487-92. PMID: 23799612
3. Kittlesen, DJ. et al. (2000) The Journal of clinical investigation 106, 1239-49. PMID: 11086025
4. Waggoner, SN. et al. (2007) Journal of leukocyte biology 82, 1407-19. PMID: 17881511
5. Ruggieri, A. et al. (2003) Virus research 97, 103-10. PMID: 14602201
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • Western blot

    Western blot analysis was performed using anti-glycoprotein E2 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant hepatitis C virus (Catalog No: VK681011)
    Lane 2: negative control

  • Bioactivity

    Detects recombinant HCV NS1/gp68/gp70/Envelope glycoprotein E2 (Catalog No: VK681011) in indirect ELISA

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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