



| 货号 | MB651207 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Mouse |
| 应用 | in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion |
| 同种型 | IgG2b, kappa |
| 克隆号 | 9D9 |
| 靶标 | CD152, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4 |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P09793 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy). |
| Note | For research use only. |

Detects CD152/CTLA4 in indirect ELISAs.

Detects recombinant mouse CD152/CTLA4 (Catalog No: MB651011) in indirect ELISA





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