Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO) (HB665016)

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概述
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产品说明书

概述

货号	HB665016
品牌	abinScience
描述	Vofatamab (HB665016) is a research-grade recombinant antibody targeting CD333. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型	IgG1-kappa
表达系统	Mammalian cells
经测试应用	WB
靶标	Fibroblast growth factor receptor 3, FGFR-3, FGFR3, JTK4, CD333
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P22607
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	MFGR1877S, MFGR-1877S, MFGR1877S, 1312305-12-6
背景	Fibroblast growth factor receptor 3 (CD333/FGFR3) is a ~87 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Required for normal development of the inner ear.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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SEC-HPLC

SEC-HPLC detection for Research Grade Vofatamab.
Bioactivity

Detects CD333/FGFR3 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Vofatamab.
Western blot

Western blot analysis was performed using anti-CD333/FGFR3 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human CD333/FGFR3 (Catalog No: HB665011)

参考文献

产品说明书

Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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实验相关试剂

Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO) (HB665016)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO) (HB665016)

概述

图片

参考文献

产品说明书

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