Anti-Human FGFR3 Reference Antibody (LY3076226, RUO) (HB665036)

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货号	HB665036
品牌	abinScience
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG
克隆号	LY3076226
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	Fibroblast growth factor receptor 3, FGFR-3, FGFR3, JTK4, CD333
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P22607
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Fibroblast growth factor receptor 3 (CD333/FGFR3) is a ~87 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Required for normal development of the inner ear.
文献	1. Kollmannsberger C, et al. A phase 1 study of LY3076226, a fibroblast growth factor receptor 3 (FGFR3) antibody-drug conjugate, in patients with advanced or metastatic cancer. Invest New Drugs. 2021 Dec;39(6):1613-1623. [HB665036]
Note	For research use only. Not suitable for clinical or therapeutic use.

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD333/FGFR3 (LY3076226)

产品说明书

Anti-Human FGFR3 Reference Antibody (LY3076226, RUO).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

V₁ (起始体积)

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Anti-Human FGFR3 Reference Antibody (LY3076226, RUO) (HB665036)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FGFR3 Reference Antibody (LY3076226, RUO) (HB665036)

概述

图片

参考文献

产品说明书

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