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Research Grade Losatuxizumab (HF004136)

价格:
规格:
  • 100ug
  • 1mg
数量:
  • 概述
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  • 参考文献
  • 产品说明书
概述
货号HF004136
品牌abinScience
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Humanized
同种型IgG1-kappa
表达系统Mammalian Cells
克隆类型Monoclonal
靶标HER1, Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, EGFR, ERBB1, ERBB
内毒素水平Please contact the lab for this information.
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P00533
状态Liquid
保存溶液0.01M PBS, pH 7.4.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
别名ABT-806, PR-1316749, 1801544-27-3
背景Losatuxizumab (ABT-806) is an anti-EGFR monoclonal antibody. Losatuxizumab binds to EGFR with EC50s of 0.96 nM for EGFR wild-type, 0.09 nM for EGFRC271A, C283A, 0.12 nM for EGFRvIII, 0.66 nM for EGFR1-501. Losatuxizumab can be used for research of EGFR-expressing cancers.
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • SEC-HPLC

    SEC-HPLC detection for Research Grade Losatuxizumab.

  • Bioactivity

    Detects EGFR/ERBB1/HER1 in indirect ELISAs.

参考文献

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