| 货号 | HV426026 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Humanized |
| 同种型 | IgG1-kappa |
| 表达系统 | Mammalian Cells |
| 克隆类型 | Monoclonal |
| 靶标 | DPEP3, Dipeptidase 3 |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | Q9H4B8 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 别名 | DC-1728001, SC-003, SC-003ADC, SC-003mAb, SC-Mab003, SC34.28ss1, Tamrintamabpamozirine, 2148325-59-9 |
| 背景 | Technetium (99mTc) pintumomab (INN) is a mouse monoclonal antibody for the imaging of adenocarcinoma. It is labelled with the radioisotope technetium-99m. • ADC: a deadly killer of platinum resistant ovarian cancer., PMID:39367438 • A mini-overview of antibody-drug conjugates in platinum-resistant ovarian cancer: A preclinical and clinical perspective., PMID:39922351 • Molecular characterization and expression of dipeptidase 3, a testis-specific membrane-bound dipeptidase: complex formation with TEX101, a germ-cell-specific antigen in the mouse testis., PMID:21724266 • Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity., PMID:32325220 • Tamrintamab pamozirine (SC-003) in patients with platinum-resistant/refractory ovarian cancer: Findings of a phase 1 study., PMID:32513564 • The testis-specifically expressed Dpep3 is not essential for male fertility in mice., PMID:31212048 • Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies., PMID:30097533 • Effects of varicocele and microsurgical varicocelectomy on the metabolites in semen., PMID:35338186 • Identification of two additional members of the membrane-bound dipeptidase family., PMID:12738806 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
SEC-HPLC detection for Research Grade Tamrintamab.
SDS-PAGE for Research Grade Tamrintamab.
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