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Research Grade Seribantumab (HB116056)

价格:
规格:
  • 100ug
  • 1mg
数量:
  • 概述
  • 图片
  • 参考文献
  • 产品说明书
概述
货号HB116056
品牌abinScience
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Human
同种型IgG2-lambda
表达系统Mammalian Cells
克隆类型Monoclonal
靶标ERBB3, HER3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, Receptor tyrosine-protein kinase erbB-3
内毒素水平Please contact the lab for this information.
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P21860
状态Liquid
保存溶液0.01M PBS, pH 7.4.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
别名MM-121, SAR256212, 1334296-12-6
背景Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models.
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • Bioactivity

    SEC-HPLC detection for Research Grade Seribantumab.

参考文献

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