



| 货号 | HV777016 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Samrotamab (HV777016) is a research-grade recombinant antibody targeting Leucine-rich repeat protein induced by beta-amyloid homolog. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 同种型 | IgG1-kappa |
| 表达系统 | Mammalian cells |
| 靶标 | Leucine-rich repeat protein induced by beta-amyloid homolog, LRRC15, Leucine-rich repeat-containing protein 15, LIB, hLib |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | Q8TF66 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | ABBV-085, PR-1498487-MMAE, PR-1498487, Samrotamabvedotin, 2052591-32-7 |
| 背景 | Leucine-rich repeat-containing protein 15 (LRRC15/LIB) is a ~64 kDa protein. (Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein. Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells. 1. Song, J. et al. (2022) PLoS biology 20, e3001805. PMID: 36228039 2. Shilts, J. et al. (2023) PLoS biology 21, e3001959. PMID: 36735681 3. Loo, L. et al. (2023) PLoS biology 21, e3001967. PMID: 36757924 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |

SEC-HPLC detection for Research Grade Samrotamab.

SDS-PAGE for Research Grade Samrotamab





24小时产品查询

扫一扫关注我们

专属渠道经理