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Research Grade Reozalimab (HV974216)

价格:
规格:
  • 100ug
  • 1mg
数量:
  • 概述

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概述
货号HV974216
品牌abinScience
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Human
同种型Ig(G1-kappa_G1-lambda2)
表达系统Mammalian Cells
克隆类型Monoclonal
靶标B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
内毒素水平Please contact the lab for this information.
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q9NZQ7 & Q15116
状态Liquid
保存溶液 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
别名Bispecific, IBI318, IBI-318, IBI318, 2445259-99-2
背景Reozalimab is a bispecific antibody targeting to PD-1/PD-L1. Reozalimab mediates antibody-dependent cell cytotoxicity in cancer research.
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • Bioactivity

    Detects PDL1 in indirect ELISA.

  • Flow CytoMetry

    Flow-cytometry using anti-human CD274 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD274 monoclonal antibody (Catalog: HV974216) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

  • Bioactivity

    Detects recombinant human PD1 (Cat No.: HS870021) in indirect ELISA.

  • Western blot

    Western blot analysis was performed using anti-CD274/PD-L1/B7-H1 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human CD274/PD-L1/B7-H1 (Catalog No: HV974011)
    Lane 2: negative control

参考文献

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