Anti-Human CD8 alpha Reference Antibody (Crefmirlimab, RUO) (HP158016)

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概述
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概述

货号	HP158016
品牌	abinScience
描述	Crefmirlimab (HP158016) is a research-grade recombinant antibody targeting CD8. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	(scFv-kappa-heavy) -h- CH3
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	T-cell surface glycoprotein CD8 alpha chain, CD8a, T-lymphocyte differentiation antigen T8/Leu-2, MAL, CD8A
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Purified by ion exchange chromatography.
Accession号	P01732
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	89Zr-IAB22M2C, IAB22M2C, 89Zr-Df-IAB22M2C, 2611099-93-3
背景	T-cell surface glycoprotein CD8 alpha chain (CD8A) is a ~25 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

Detects CD8A in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Crefmirlimab.

参考文献

产品说明书

Anti-Human CD8 alpha Reference Antibody (Crefmirlimab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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实验相关试剂

Anti-Human CD8 alpha Reference Antibody (Crefmirlimab, RUO) (HP158016)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD8 alpha Reference Antibody (Crefmirlimab, RUO) (HP158016)

概述

图片

参考文献

产品说明书

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