Anti-Human IL-11R alpha Reference Antibody (X209, RUO) (HC604016)

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概述
图片
参考文献
产品说明书

概述

货号

HC604016

品牌

abinScience

描述

Anti-Human IL11RA Antibody (X209) (HC604016) is a research-grade recombinant antibody targeting IL-11RA. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

种属反应性

Human

应用

ELISA, WB, Bioactivity: FACS, Functional assay, Research in vivo

同种型

IgG4, kappa

克隆号

X209

表达系统

Mammalian cells

经测试应用

靶标

IL-11RA, sIL-11R, Interleukin-11 receptor subunit alpha, sIL-11RA, IL11RA, IL-11R-alpha, IL-11R subunit alpha, IL-11 receptor subunit alpha, sIL11RA

内毒素水平

< 10 EU/mg

纯度

>95% purity as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

Q14626

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

EnX209

背景

Interleukin-11 receptor subunit alpha (IL11RA) is a ~45 kDa protein. Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.

Note

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Human IgG4 (S228P & L235E) Recombinant Isotype Control Antibody (HyHEL-10) (HP614107)
Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)

图片

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human IL11RA Antibody (X209).
Bioactivity

Detects Recombinant Human IL11RA Protein, C-His (Cat No.: HC604011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-IL11RA monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human IL11RA (Catalog No: HC604011)

参考文献

产品说明书

Anti-Human IL-11R alpha Reference Antibody (X209, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human IL-11R alpha Reference Antibody (X209, RUO) (HC604016)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human IL-11R alpha Reference Antibody (X209, RUO) (HC604016)

概述

图片

参考文献

产品说明书

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